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Multiple Choice

Lisinopril belongs to which class of antihypertensive drugs?

Lisinopril is an ACE inhibitor. It blocks angiotensin-converting enzyme, which normally changes angiotensin I into angiotensin II. With less angiotensin II, blood vessels relax (vasodilation) and aldosterone secretion drops, reducing sodium and water retention—so blood pressure falls. This mechanism is different from beta blockers (which slow the heart by blocking adrenergic receptors), diuretics (which lower blood pressure by increasing urine output to reduce blood volume), and calcium channel blockers (which limit calcium entry to relax vessels and weaken heart contractions). Sometimes ACE inhibitors can cause a cough or, less commonly, hyperkalemia or angioedema.

Lisinopril is an ACE inhibitor. It blocks angiotensin-converting enzyme, which normally changes angiotensin I into angiotensin II. With less angiotensin II, blood vessels relax (vasodilation) and aldosterone secretion drops, reducing sodium and water retention—so blood pressure falls. This mechanism is different from beta blockers (which slow the heart by blocking adrenergic receptors), diuretics (which lower blood pressure by increasing urine output to reduce blood volume), and calcium channel blockers (which limit calcium entry to relax vessels and weaken heart contractions). Sometimes ACE inhibitors can cause a cough or, less commonly, hyperkalemia or angioedema.