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Multiple Choice

Which of the following can cause respiratory alkalosis?

Respiratory alkalosis happens when you blow off carbon dioxide faster than your body produces it, which lowers CO2 in the blood and raises pH. Anything that increases ventilation beyond what the body needs can cause this shift. Mechanical ventilation can do exactly that: if the ventilator is set to high rate or large tidal volumes, it can drive excess breathing (hyperventilation), rapidly reducing CO2 levels and leading to respiratory alkalosis. In contrast, hypoventilation traps more CO2 in the blood, causing respiratory acidosis. Increased PCO2 directly causes acidosis, not alkalosis. Metabolic acidosis is a metabolic problem that the body tries to compensate for by hyperventilating; this respiratory response can produce respiratory alkalosis, but the primary driver is the metabolic disturbance, not a direct respiratory cause. So the scenario most likely to produce respiratory alkalosis directly is mechanical ventilation with excessive ventilation.

Respiratory alkalosis happens when you blow off carbon dioxide faster than your body produces it, which lowers CO2 in the blood and raises pH. Anything that increases ventilation beyond what the body needs can cause this shift.

Mechanical ventilation can do exactly that: if the ventilator is set to high rate or large tidal volumes, it can drive excess breathing (hyperventilation), rapidly reducing CO2 levels and leading to respiratory alkalosis.

In contrast, hypoventilation traps more CO2 in the blood, causing respiratory acidosis. Increased PCO2 directly causes acidosis, not alkalosis. Metabolic acidosis is a metabolic problem that the body tries to compensate for by hyperventilating; this respiratory response can produce respiratory alkalosis, but the primary driver is the metabolic disturbance, not a direct respiratory cause. So the scenario most likely to produce respiratory alkalosis directly is mechanical ventilation with excessive ventilation.