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Multiple Choice

Which of the following is true about ACE inhibitors?

ACE inhibitors block the enzyme that converts angiotensin I to angiotensin II, leading to vasodilation and reduced aldosterone-driven sodium and water retention. This mechanism lowers blood pressure and decreases workload on the heart. Drugs in this class include lisinopril and captopril, which is why this statement is true. They are not beta blockers, which slow the heart and reduce its workload through a different mechanism, and they are not ARBs, which block angiotensin II receptors (examples include losartan and valsartan). They’re also not primarily diuretics, although they can cause mild diuresis in some patients. A common related side effect is a cough from bradykinin buildup.

ACE inhibitors block the enzyme that converts angiotensin I to angiotensin II, leading to vasodilation and reduced aldosterone-driven sodium and water retention. This mechanism lowers blood pressure and decreases workload on the heart. Drugs in this class include lisinopril and captopril, which is why this statement is true. They are not beta blockers, which slow the heart and reduce its workload through a different mechanism, and they are not ARBs, which block angiotensin II receptors (examples include losartan and valsartan). They’re also not primarily diuretics, although they can cause mild diuresis in some patients. A common related side effect is a cough from bradykinin buildup.