Which of the following is a calcium-channel blocker used for hypertension?

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Multiple Choice

Which of the following is a calcium-channel blocker used for hypertension?

Calcium-channel blockers work by blocking L-type calcium channels in smooth muscle and heart, which lowers intracellular calcium. That causes arterial relaxation and reduced peripheral resistance, lowering blood pressure. In the heart, less calcium also slows AV nodal conduction and can reduce heart rate, aiding rhythm control in some cases. Diltiazem is a non-dihydropyridine calcium-channel blocker. It lowers blood pressure mainly through vasodilation and also slows heart rate and AV conduction, making it useful for hypertension and certain tachyarrhythmias. The other medications listed work via different mechanisms: one is a diuretic that reduces blood volume, and the other is an ACE inhibitor that blocks the renin-angiotensin system.

Calcium-channel blockers work by blocking L-type calcium channels in smooth muscle and heart, which lowers intracellular calcium. That causes arterial relaxation and reduced peripheral resistance, lowering blood pressure. In the heart, less calcium also slows AV nodal conduction and can reduce heart rate, aiding rhythm control in some cases.

Diltiazem is a non-dihydropyridine calcium-channel blocker. It lowers blood pressure mainly through vasodilation and also slows heart rate and AV conduction, making it useful for hypertension and certain tachyarrhythmias. The other medications listed work via different mechanisms: one is a diuretic that reduces blood volume, and the other is an ACE inhibitor that blocks the renin-angiotensin system.

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