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Multiple Choice

Which treatment is commonly used for Type I hypersensitivity reactions?

Epinephrine is the first-line treatment for acute Type I hypersensitivity reactions because it quickly counteracts the life-threatening effects of IgE-mediated responses. It works on multiple receptors to reverse airway constriction and swelling: alpha-adrenergic effects cause vasoconstriction, reducing edema and improving blood pressure; beta-1 effects support heart output; beta-2 effects relax bronchial smooth muscle to relieve bronchospasm. This rapid action addresses the core dangers of anaphylaxis, which is the severe form of this reaction. Allergen avoidance helps prevent future reactions by reducing exposure, but it does not treat an active episode. Plasmapheresis and interferon aren’t standard treatments for acute Type I hypersensitivity; plasmapheresis is used for certain autoimmune conditions, and interferon is used in other contexts, not immediate allergic reactions.

Epinephrine is the first-line treatment for acute Type I hypersensitivity reactions because it quickly counteracts the life-threatening effects of IgE-mediated responses. It works on multiple receptors to reverse airway constriction and swelling: alpha-adrenergic effects cause vasoconstriction, reducing edema and improving blood pressure; beta-1 effects support heart output; beta-2 effects relax bronchial smooth muscle to relieve bronchospasm. This rapid action addresses the core dangers of anaphylaxis, which is the severe form of this reaction.

Allergen avoidance helps prevent future reactions by reducing exposure, but it does not treat an active episode. Plasmapheresis and interferon aren’t standard treatments for acute Type I hypersensitivity; plasmapheresis is used for certain autoimmune conditions, and interferon is used in other contexts, not immediate allergic reactions.